References
1. Gordon T, Castelli WP, Hjortland MC et al. High
density lipoprotein as a protective factor against coronary heart disease.
The Framingham Study. Am J Med 1977;
62:707714.
2. Gordon DJ, Probstfield JL, Garrison RJ et al.
High-density
lipoprotein cholesterol and cardiovascular disease. Four prospective American
studies. Circulation 1989;
79:815.
3. Castelli WP. Cholesterol and lipids in the risk of coronary heart
disease–the Framingham Heart Study. Can J Cardiol 1988;
4(Suppl
A):5A10A.
4. Abbott RD, Wilson PW, Kannel WB et al.
High density
lipoprotein cholesterol, total cholesterol screening, and myocardial infarction.
The Framingham Study. Arteriosclerosis 1988;
8:207211.
5. Stampfer MJ, Sacks FM, Salvini S et al.
A prospective
study of cholesterol, apolipoproteins, and the risk of myocardial infarction.
N Engl J Med 1991;
325:373381.
6. Assmann G, Schulte H. Relation of high-density lipoprotein cholesterol
and triglycerides to incidence of atherosclerotic coronary artery disease
(the PROCAM experience). Am J Cardiol 1992;
70:733737.
7. Bolibar I, von Eckardstein A, Assmann G et al.
Short-term prognostic
value of lipid measurements in patients with angina pectoris. The ECAT Angina
Pectoris Study Group: European Concerted Action on Thrombosis and Disabilities.
Thromb Haemost 2000;
84:955960.
8. Pekkanen J, Linn S, Heiss G et al. Ten-year mortality from
cardiovascular disease in relation to cholesterol level among men with and
without preexisting cardiovascular disease. N Engl J Med 1990;
322:17001707.
9. Salonen R, Seppanen K, Rauramaa I et al.
Prevalence of
carotid atherosclerosis and serum cholesterol levels in eastern Finland. Arteriosclerosis 1988;
8:788792.
10. Miller M, Seidler A, Kwiterovich PO et al.
Long-term predictors
of subsequent cardiovascular events with coronary artery disease and 'desirable'
levels of plasma total cholesterol. Circulation
1992; 86:11651170.
11. Shah PK, Amin J. Low high density lipoprotein level is associated
with increased restenosis rate after coronary angioplasty. Circulation
1992; 85:12791285.
12. Violaris AG, Melkert R, Serruys PW. Influence of serum cholesterol
and cholesterol subfractions on restenosis after successful coronary angioplasty.
A quantitative angiographic analysis of 3336 lesions. Circulation
1994; 90:22672279.
13. Roth A, Eshchar Y, Keren G et al. Serum lipids and restenosis
after successful percutaneous transluminal coronary angioplasty. Ichilov Magnesium
Study Group. Am J Cardiol 1994;
73:11541158.
14. Dzavik V, Teo KK, Yokoyama S et al.
Effect of serum
lipid concentrations on restenosis after successful de novo percutaneous transluminal
coronary angioplasty in patients with total cholesterol 160 to 240 mg/dl and
triglycerides < 350 mg/dl. Am
J Cardiol 1995; 75:936938.
15. Frick MH, Elo O, Haapa K et al. Helsinki Heart Study: primary-prevention
trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment,
changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987; 317:12371245.
16. Rubins HB, Robins SJ, Collins D. The Veteran Affairs High-Density
Lipoprotein Intervention Trial: baseline characteristics of normocholesterolemic
men with coronary artery disease and low levels of high-density lipoprotein
cholesterol. Am J Cardiol 1996;
78:572575.
17. Rubins HB, Robins SJ, Collins D et al.
Gemfibrozil for
the secondary prevention of coronary heart disease in men with low levels
of high-density lipoprotein cholesterol. N
Engl J Med 1999; 341:410418.
18. Downs JR, Clearfield M, Weis S et al.
Primary prevention
of acute coronary events with lovastatin in men and women with average cholesterol
levels. Results of AFCAPS/TexCAPS. JAMA 1998; 279:16151622.
19. DAIS Investigators. Effect of fenofibrate on progression of coronary-artery
disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study,
a randomised study. Lancet 2001;
357:905910.
20. Heart Protection Study Collaborative Group. MRC/BHF Heart Protection
Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals:
a randomised placebo-controlled trial. Lancet 2002;
360:722.
21. 4S Study Group. Randomised trial of cholesterol lowering in 4444 patients
with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S).
Lancet 1994;
344:13831389.
22. LIPID Study Group. Prevention of cardiovascular events and death with
pravastatin in patients with coronary heart disease and a broad range of initial
cholesterol levels. N Engl J Med 1998;
339:13491357.
23. Sacks FM, Pfeffer MA, Moye LA et al.
The effect of
pravastatin on coronary events after myocardial infarction in patients with
average cholesterol levels. Cholesterol and Recurrent Events Trial Investigators.
N Engl J Med 1996;
335:10011009.
24. WOSCOPS Study Group. Influence of pravastatin and plasma lipids on clinical
events in the West of Scotland Coronary Prevention Study (WOSCOPS). Circulation 1998; 97:14401445.
25. Sever PS, Dahlof B, Poulter NR et al.
Prevention of
coronary and stroke events with atorvastatin in hypertensive patients who
have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian
Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised
controlled trial. Lancet
2003; 361:11491158.
26. Serruys PW, De Feyter PJ, Benghozi R et al.
The Lescol(R)
Intervention Prevention Study (LIPS): a double-blind, placebo-controlled,
randomized trial of the long-term effects of fluvastatin after successful
transcatheter therapy in patients with coronary heart disease. Int J Cardiovasc Intervent 2001; 4:165172.
27. Sacks FM. The role of high-density lipoprotein (HDL) cholesterol in
the prevention and treatment of coronary heart disease: expert group recommendations.
Am J Cardiol 2002; 90:139143.
28. Zhao XQ, Morse JS, Dowdy AA et al. Safety and tolerability
of simvastatin plus niacin in patients with coronary artery disease and low
high-density lipoprotein cholesterol (the HDL Atherosclerosis Treatment Study).
Am J Cardiol 2004; 93:307312.
29. Assmann G. Lipid Metabolism and Atherosclerosis. New
York: Schattauer; 1982.
30. von Eckardstein A, Huang Y, Assmann G. Physiological role and
clinical relevance of high-density lipoprotein subclasses. Curr Opin Lipidol 1994;
5:404416.
31. Skinner ER. High-density lipoprotein subclasses. Curr
Opin Lipidol 1994; 5:241247.
32. Anantharamaiah GM, Brouillette CG, Engler JA et al.
Role of amphipathic
helixes in HDL structure/function. Adv Exp Med Biol 1991; 285:131140.
33. Brouillette CG, Anantharamaiah GM. Structural models of human
apolipoprotein A-I. Biochim Biophys Acta 1995; 1256:103129.
34. Brouillette CG, Anantharamaiah GM, Engler JA et al.
Structural models
of human apolipoprotein A-I: a critical analysis and review. Biochim Biophys Acta 2001; 1531:446.
35. Frank PG, Marcel YL. Apolipoprotein A-I: structure-function relationships.
J Lipid Res 2000; 41:853872.
36. Segrest JP, Li L, Anantharamaiah GM et al.
Structure and
function of apolipoprotein A-I and high-density lipoprotein. Curr Opin Lipidol 2000; 11:105115.
37. Klon AE, Segrest JP, Harvey SC. Comparative models for
human apolipoprotein A-I bound to lipid in discoidal high-density lipoprotein
particles. Biochemistry 2002; 41:1089510905.
38. Navab M, Hama SY, Hough GP et al. High density associated
enzymes: their role in vascular biology. Curr Opin Lipidol 1998;
9:449456.
39. Peelman F, Vandekerckhove J, Rosseneu M. Structure and function
of lecithin cholesterol acyl transferase: new insights from structural predictions
and animal models. Curr Opin Lipidol
2000; 11:155160.
40. Jonas A. Lecithin cholesterol acyltransferase.
Biochim Biophys Acta 2000; 1529:245256.
41. Jin W, Marchadier D, Rader DJ. Lipases and HDL metabolism.
Trends Endocrinol Metab 2002; 13:174178.
42. Tall AR. Plasma cholesteryl ester transfer protein and high-density
lipoproteins: new insights from molecular genetic studies. J Intern Med 1995; 237:512.
43. Morton RE. Cholesteryl ester transfer protein and its plasma
regulator: lipid transfer inhibitor protein. Curr Opin Lipidol 1999;
10:321327.
44. Barter PJ, Brewer HB Jr, Chapman MJ et al.
Cholesteryl ester
transfer protein: a novel target for raising HDL and inhibiting atherosclerosis.
Arterioscler Thromb Vasc
Biol 2003; 23:160167.
45. Tall AR, Lalanne F. Phospholipid transfer protein and atherosclerosis.
Arterioscler Thromb Vasc Biol 2003;
23:14841485.
46. Huuskonen J, Olkkonen VM, Jauhiainen M et al.
The impact of
phospholipid transfer protein (PLTP) on HDL metabolism. Atherosclerosis 2001; 155:269281.
47. van Tol A. Phospholipid transfer protein. Curr
Opin Lipidol 2002; 13:135139.
48. Durrington PN, Mackness B, Mackness MI. Paraoxonase and atherosclerosis.
Arterioscler Thromb Vasc Biol 2001;
21:473480.
49. Mackness MI, Mackness B, Durrington PN. Paraoxonase and coronary
heart disease. Atheroscler Suppl 2002; 3:4955.
50. Mackness B, Durrington PN, Mackness MI. The paraoxonase gene family
and coronary heart disease. Curr Opin Lipidol 2002;
13:357362.
51. Getz GS, Reardon CA. Paraoxonase, a cardioprotective enzyme: continuing
issues. Curr Opin Lipidol 2004;
15:261267.
52. Mertens A, Holvoet P. Oxidized LDL and HDL: antagonists in atherothrombosis.
FASEB J 2001; 15:20732084.
53. Tselepis AD, Chapman JM. Inflammation, bioactive lipids and atherosclerosis:
potential roles of a lipoprotein-associated phospholipase A2, platelet activating
factor-acetylhydrolase. Atheroscler Suppl 2002;
3:5768.
54. Voetsch B, Loscalzo J. Genetic determinants of arterial thrombosis. Arterioscler Thromb Vasc Biol 2004;
24:216229.
55. Maytin M, Leopold J, Loscalzo J. Oxidant stress in the vasculature.
Curr Atheroscler Rep 1999; 1:156164.
56. Niessen HW, Krijnen PA, Visser CA et al.
Type II secretory
phospholipase A2 in cardiovascular disease: a mediator in atherosclerosis
and ischemic damage to cardiomyocytes? Cardiovasc Res 2003; 60:6877.
57. Hannuksela ML, Liinamaa MJ, Kesaniemi YA et al.
Relation of polymorphisms
in the cholesteryl ester transfer protein gene to transfer protein activity
and plasma lipoprotein levels in alcohol drinkers. Atherosclerosis 1994; 110:3544.
58. Lagrost L, Athias A, Herbeth B et al.
Opposite effects
of cholesteryl ester transfer protein and phospholipid transfer protein on
the size distribution of plasma high density lipoproteins. Physiological relevance
in alcoholic patients. J Biol Chem 1996;
271:1905819065.
59. Borggreve SE, De Vries R, Dullaart RP. Alterations in high-density
lipoprotein metabolism and reverse cholesterol transport in insulin resistance
and type 2 diabetes mellitus: role of lipolytic enzymes, lecithin:cholesterol
acyltransferase and lipid transfer proteins. Eur J Clin Invest 2003;
33:10511069.
60. Colhoun HM, Scheek LM, Rubens MB et al.
Lipid transfer
protein activities in type 1 diabetic patients without renal failure and nondiabetic
control subjects and their association with coronary artery calcification.
Diabetes 2001;
50:652659.
61. Riemens SC, van Tol A, Sluiter WJ et al.
Plasma phospholipid
transfer protein activity is related to insulin resistance: impaired acute
lowering by insulin in obese type II diabetic patients. Diabetologia 1998; 41:929934.
62. Kahri J, Vuorinen-Markkola H, Tilly-Kiesi M et al.
Effect of gemfibrozil
on high density lipoprotein subspecies in non-insulin dependent diabetes mellitus.
Relations to lipolytic enzymes and to the cholesteryl ester transfer protein
activity. Atherosclerosis 1993;
102:7989.
63. Colvin PL, Parks JS. Metabolism of high density lipoprotein subfractions.
Curr Opin Lipidol 1999; 10:309314.
64. Leroy A, Dallongeville J, Fruchart JC. Apolipoprotein A-I-containing
lipoproteins and atherosclerosis. Curr Opin Lipidol 1995;
6:281285.
65. Forte TM, McCall MR. The role of apolipoprotein A-I-containing lipoproteins
in atherosclerosis. Curr Opin Lipidol 1994;
5:354364.
66. Duverger N, Rader D, Duchateau P et al.
Biochemical characterization
of the three major subclasses of lipoprotein A-I preparatively isolated from
human plasma. Biochemistry 1993;
32:1237212379.
67. von Eckardstein A, Nofer JR, Assmann G. Acceleration of reverse
cholesterol transport. Curr Opin Cardiol 2000; 15:348354.
68. Barrans A, Jaspard B, Barbaras R et al.
Pre-beta HDL:
structure and metabolism. Biochim Biophys Acta
1996; 1300:7385.
69. Castro GR, Fielding CJ. Early incorporation of cell-derived cholesterol into
pre-beta-migrating high-density lipoprotein. Biochemistry 1988;
27:2529.
70. Asztalos BF, Sloop CH, Wong L et al.
Comparison of
apo A-I-containing subpopulations of dog plasma and prenodal peripheral lymph:
evidence for alteration in subpopulations in the interstitial space. Biochim Biophys Acta
1993; 1169:301304.
71. Asztalos BF, Sloop CH, Wong L et al.
Two-dimensional
electrophoresis of plasma lipoproteins: recognition of new apo A-I-containing
subpopulations. Biochim Biophys Acta
1993; 1169:291300.
72. Nanjee MN, Cooke CJ, Olszewski WL et al.
Concentrations
of electrophoretic and size subclasses of apolipoprotein A-I-containing particles
in human peripheral lymph. Arterioscler
Thromb Vasc Biol 2000; 20:21482155.
73. Tailleux A, Bouly M, Luc G et al. Decreased susceptibility
to diet-induced atherosclerosis in human apolipoprotein A-II transgenic mice.
Arterioscler Thromb Vasc Biol 2000;
20:24532458.
74. Ikewaki K, Zech LA, Brewer HB Jr et al. ApoA-II kinetics in humans
using endogenous labelling with stable isotopes: slower turnover of apoA-II
compared with the exogenous radiotracer method. J Lipid Res 1996;
37:399407.
75. Ikewaki K, Zech LA, Kindt M et al. Apolipoprotein A-II production
rate is a major factor regulating the distribution of apolipoprotein A-I among
HDL subclasses LpA-I and LpA-I:A-II in normolipidemic humans. Arterioscler
Thromb Vasc Biol 1995; 15:306312.
76. Labeur C, Lambert G, Van Cauteren T et al.
Displacement
of apo A-I from HDL by apo A-II or its C-terminal helix promotes the formation
of pre-beta1 migrating particles and decreases LCAT activation. Atherosclerosis 1998; 139:351362.
77. Hime NJ, Barter PJ, Rye KA. The influence of apolipoproteins on the hepatic lipase-mediated
hydrolysis of high density lipoprotein phospholipid and triacylglycerol. J Biol Chem 1998;
273:2719127198.
78. Lagrost L, Persegol L, Lallemant C et al.
Influence of
apolipoprotein composition of high density lipoprotein particles on cholesteryl
ester transfer protein activity. Particles containing various proportions
of apolipoproteins AI and AII. J Biol Chem 1994;
269:31893197.
79. Boisfer E, Lambert G, Atger V et al.
Overexpression
of human apolipoprotein A-II in mice induces hypertriglyceridemia due to defective
very low density lipoprotein hydrolysis. J
Biol Chem 1999; 274:1156411572.
80. McCall MR, Nichols AV, Blanche PJ et al.
Lecithin:cholesterol
acyltransferase-induced transformation of HepG2 lipoproteins. J Lipid Res 1989;
30:15791589.
81. Yamazaki S, Mitsunaga T, Furukawa T et al.
Interaction of
lecithin-cholesterol acyltransferase with human plasma lipoproteins and with
lecithin-cholesterol vesicles. J
Biol Chem 1983; 258:58475853.
82. Nazih H, Nazih-Sanderson F, Krempf M et al.
Butyrate stimulates
ApoA-IV-containing lipoprotein secretion in differentiated Caco-2 cells: role
in cholesterol efflux. J Cell Biochem 2001;
83:230238.
83. Danielsen EM, Hansen GH, Poulsen MD. Apical secretion of apolipoproteins
from enterocytes. J Cell Biol 1993;
120:13471356.
84. Castle CK, Page ME, Marotti KR et al.
Secretion of
pre-beta-migrating apoA-I by cynomolgus monkey hepatocytes in culture. J Lipid Res 1991;
32:439447.
85. Thrift RN, Forte TM, Cahoon BE et al.
Characterization
of lipoproteins produced by the human liver cell line, Hep G2, under defined
conditions. J Lipid Res 1986;
27:236250.
86. Barrans A, Collet X, Barbaras R et al.
Hepatic lipase
induces the formation of pre-beta 1 high density lipoprotein (HDL) from triacylglycerol-rich
HDL2. A study comparing liver perfusion to in vitro incubation with lipases.
J Biol Chem 1994;
269:1157211577.
87. Francone OL, Royer L, Haghpassand M. Increased prebeta-HDL levels,
cholesterol efflux, and LCAT-mediated esterification in mice expressing the
human cholesteryl ester transfer protein (CETP) and human apolipoprotein A-I
(apoA-I) transgenes. J Lipid Res 1996;
37:12681277.
88. von Eckardstein A, Jauhiainen M, Huang Y et al.
Phospholipid
transfer protein mediated conversion of high density lipoproteins generates
pre beta 1-HDL. Biochim Biophys Acta
1996; 1301:255262.
89. Eisenberg S. High density lipoprotein metabolism. J
Lipid Res 1984; 25:10171058.
90. Denis M, Haidar B, Marcil M et al. Molecular and cellular
physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter
A1 (ABCA1). J Biol Chem 2004; 279:73847394.
91. Favari E, Lee M, Calabresi L et al.
Depletion of
pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette
transporter A1- but not scavenger receptor class B type I-mediated lipid efflux
to high density lipoprotein. J Biol Chem 2004;
279:99309936.
92. Hara H, Yokoyama S. Interaction of free apolipoproteins with macrophages.
Formation of high density lipoprotein-like lipoproteins and reduction of cellular
cholesterol. J Biol Chem 1991;
266:30803086.
93. Huang Y, von Eckardstein A, Wu S et al.
A plasma lipoprotein
containing only apolipoprotein E and with gamma mobility on electrophoresis
releases cholesterol from cells. Proc Natl Acad Sci USA 1994; 91:18341838.
94. Asztalos B, Zhang W, Roheim PS et al.
Role of free
apolipoprotein A-I in cholesterol efflux. Formation of pre-alpha-migrating
high-density lipoprotein particles. Arterioscler Thromb Vasc
Biol 1997; 17:16301636.
95. Forte TM, Bielicki JK, Knoff L et al.
Structural relationships
between nascent apoA-I-containing particles that are extracellularly assembled
in cell culture. J
Lipid Res 1996; 37:10761085.
96. von Eckardstein A, Huang Y, Wu S et al.
Lipoproteins
containing apolipoprotein A-IV but not apolipoprotein A-I take up and esterify
cell-derived cholesterol in plasma. Arterioscler
Thromb Vasc Biol 1995; 15:17551763.
97. Musliner TA, Long MD, Forte TM et al.
Dissociation
of high density lipoprotein precursors from apolipoprotein B-containing lipoproteins
in the presence of unesterified fatty acids and a source of apolipoprotein
A-I. J Lipid Res 1991;
32:917933.
98. Oram JF, Yokoyama S. Apolipoprotein-mediated removal of cellular cholesterol
and phospholipids. J Lipid Res 1996;
37:24732491.
99. Lambert G, Decout A, Vanloo B et al.
The C-terminal
helix of human apolipoprotein AII promotes the fusion of unilamellar liposomes
and displaces apolipoprotein AI from high-density lipoproteins. Eur J Biochem 1998; 253:328338.
100. Clay MA, Pyle DH, Rye KA et al. Formation of spherical,
reconstituted high density lipoproteins containing both apolipoproteins A-I
and A-II is mediated by lecithin:cholesterol acyltransferase. J Biol Chem 2000; 375:90199025.
101. Rye KA, Clay MA, Barter PJ. Remodelling of high density lipoproteins by plasma
factors. Atherosclerosis 1999;
145:227238.
102. Barter PJ. Hugh Sinclair Lecture: the regulation and remodelling
of HDL by plasma factors. Atheroscler Suppl 2002;
3:3947.
103. Trigatti B, Rigotti A, Krieger M. The role of the high-density
lipoprotein receptor SR-BI in cholesterol metabolism. Curr Opin Lipidol 2000;
11:123131.
104. Krieger M. Charting the fate of the 'good cholesterol': identification
and characterization of the high-density lipoprotein receptor SR-B1. Annu Rev Biochem 1999; 68:523558.
105. Acton S, Rigotti A, Landschulz KT et al.
Identification
of scavenger receptor AR-BI as a high density lipoprotein receptor. Science 1996; 271:518520.
106. Landschulz KT, Pathak RK, Rigotti A et al.
Regulation of
scavenger receptor, class B, type I, a high density lipoprotein receptor,
in liver and steroidogenic tissues of the rat. J
Clin Invest 1996; 98:984995.
107. Hirano K, Yamashita S, Nakagawa Y et al.
Expression of
human scavenger receptor class B type I in cultured human monocyte-derived
macrophages and atherosclerotic lesions. Circ
Res 1999; 85:108116.
108. Yeh YC, Hwang GY, Liu IP et al. Identification and expression
of scavenger receptor SR-BI in endothelial cells and smooth muscle cells of
rat aorta in vitro and in vivo. Atherosclerosis 2002;
161:95103.
109. Babitt J, Trigatti B, Rigotti A et al.
Murine SR-BI,
a high density lipoprotein receptor that mediates selective lipid uptake,
is a N-glycosylated and fatty acylated and colocalizes with plasma membrane
caveolae. J Biol Chem 1997;
272:1324213249.
110. Silver DL, Wang N, Xiao X et al. High density lipoprotein
(HDL) particle uptake mediated by scavenger receptor class B type I results
in selective sorting of HDL cholesterol from protein and polarized cholesterol
secretion. J Biol Chem 2001; 276:2528725293.
111. Rhainds D, Bourgeois P, Bourret G et al.
Localization
and regulation of SR-BI in membrane rafts of HepG2 cells. J Cell Sci 2004; 117:30953105.
112. Liadaki KN, Liu T, Xu S et al. Binding of high density
lipoprotein (HDL) and discoidal reconstituted HDL to the HDL receptor scavenger
receptor class B type I. Effect of lipid association and apo A-I mutations
on receptor binding. J Biol Chem 2000;
275:2126221271.
113. Xu S, Laccotripe M, Huang X et al.
Apolipoproteins
of HDL can directly mediate binding to the scavenger receptor that mediates
selective lipid uptake. J Lipid Res 1997;
38:12891298.
114. Ohgami N, Nagai R, Miyazaki A et al.
Scavenger receptor
class B type I-mediated reverse cholesterol transport is inhibited by advanced
glycation end products. J Biol Chem 2001;
276:1334813355.
115. Rigotti A, Acton SL, Krieger M. The class B scavenger receptors
SR-BI and CD36 are receptors for anionic phospholipids. J Biol Chem 1995; 270:1622116224.
116. Acton SL, Scherer PE, Lodish HF et al.
Expression cloning
of SR-BI, a CD36-related class B scavenger receptor. J Biol Chem 1994; 26 9:2100321009.
117. Marsche G, Zimmermann R, Horiuchi S et al.
Class B scavenger
receptors CD36 and SR-BI are receptors for hypochlorite-modified low density
lipoprotein. J Biol Chem 2003;
278:4756247570.
118. Fluiter K, van der Westhuijzen DR, van Berkel TJ. In vivo regulation of scavenger
receptor BI and the selective uptake of high density lipoprotein cholesteryl
esters in rat liver parenchymal and Kupffer cells. J
Biol Chem 1998; 273:84348438.
119. Connelly MA, Klein SM, Azhar S et al.
Comparison of
class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows
that both receptors mediate high density lipoprotein-cholesteryl ester selective
uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake.
J Biol Chem 1999;
274:4147.
120. Rodrigueza WV, Thuahnai ST, Temel RE et al.
Mechanism of
scavenger receptor class B type I-mediated selective uptake of cholesteryl
esters from high density lipoprotein to adrenal cells. J Biol Chem 1999; 274:2034420350.
121. Spady DK, Kearney DM, Hobbs HH. Polyunsaturated fatty acids up-regulate
hepatic scavenger receptor B1 (SR-BI) expression and HDL cholesteryl ester
uptake in the hamster. J Lipid Res 1999; 40:13841394.
122. Azzi A, Gysin R, Kempna P et al. Regulation of gene expression
by alpha-tocopherol. Biol Chem 2004; 385:585591.
123. Cao WM, Murao K, Imachi H et al. Insulin-like growth factor-I
regulation hepatic scavenger receptor class BI. Endocrinology 2004; 145:55405547.
124. Mardones P, Pilon A, Bouly M et al. Fibrates down-regulate
hepatic scavenger receptor class B type I protein expression in mice. J
Biol Chem 2003; 278:78847890.
125. Lambert G, Amar MJ, Guo G et al. The farnesoid X-receptor
is an essential regulator of cholesterol homeostasis. J Biol Chem 2003;
278:25632570.
126. Malerod L, Juvet LK, Hanssen-Bauer A et al. Oxysterol-activated
LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes.
Biochem Biophys Res Commun 2002; 299:916923.
127. Silver DL, Wang N, Vogel S. Identification of small PDZK1-associated
protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein
levels. J Biol Chem 2003; 278:2852828532.
128. Silver DL. A carboxyl-terminal PDZ-interacting domain of scavenger
receptor B, type I is essential for cell surface expression in liver. J
Biol Chem 2002; 277:3404234047.
129. Kocher O, Yesilaltay A, Cirovic C et al. Targeted disruption
of the PDZK1 gene in mice causes tissue-specific depletion of the high density
lipoprotein receptor class B type I and altered lipoprotein metabolism. J
Biol Chem 2003; 278:5282052825.
130. Frank PG, Marcel YL, Connelly MA et al. Stabilization of caveolin-1
by cellular cholesterol and scavenger receptor class B type I. Biochemistry
2002; 41:1193111940.
131. Matveev S, Uittenbogaard A, van der Westhuyzen D et al. Caveolin-1
negatively regulates SR-BI mediated selective uptake of high-density lipoprotein-derived
cholesteryl ester. Eur J Biochem 2001; 268:56095616.
132. Lambert G, Chase MB, Dugi K et al. Hepatic lipase promotes
the selective uptake of high density lipoprotein-cholesteryl esters via the
scavenger receptor B1. J Lipid Res 1999; 40:12941303.
133. Collet X, Tall AR, Serajuddin H et al. Remodeling of HDL by
CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake
of HDL CE by cells expressing scavenger receptor B-I. J Lipid Res 1999;
40:11851193.
134. Ji Y, Jian B, Wang N et al. Scavenger receptor BI promotes
high density lipoprotein-mediated cellular cholesterol efflux. J Biol
Chem 1997; 272:2098220985.
135. Yancey PG, de la Llera-Moya M, Swarnakar S et al. High density
lipoprotein phospholipid composition is a major determinant of the bi-directional
flux and net movement of cellular free cholesterol mediated by scavenger receptor
BI. J Biol Chem 2000; 275:3659636604.
136. Thuahnai ST, Lund-Katz S, Dhanasekaran P et al. Scavenger
receptor class B type I-mediated cholesteryl ester-selective uptake and efflux
of unesterified cholesterol. Influence of high density lipoprotein size and
structure. J Biol Chem 2004; 279:1244812455.
137. Choi SY, Hirata K, Ishida T et al. Endothelial lipase: a new
lipase on the block. J Lipid Res 2002; 43:17631769.
138. McCoy MG, Sun GS, Marchadier B et al. Characterization of
the lipolytic activity of endothelial lipase. J Lipid Res 2002;
43:921929.
139. deLemos AS, Wolfe ML, Long CJ et al. Identification of genetic
variants in endothelial lipase in persons with elevated high-density lipoprotein
cholesterol. Circulation 2002; 106:13211326.
140. Maugeais C, Tietge UJ, Broedl UC et al. Dose-dependent acceleration
of high-density lipoprotein catabolism by endothelial lipase. Circulation
2003; 108:21212126.
141. Jin W, Millar JS, Broedl U et al. Inhibition of endothelial
lipase causes increased HDL cholesterol levels in vivo. J Clin Invest
2003; 111:357362.
142. Jaross W, Eckey R, Medschikowski M. Biological effects of secretory
phospholipase A(2) group IIA on lipoproteins and in atherogenesis. Eur
J Clin Invest 2002; 32:383393.
143. Ivandic B, Castellani LW, Wang XP et al. Role of group II
secretory phospholipase A2 in atherosclerosis: 1. Increased atherogenesis
and altered lipoproteins in transgenic mice expressing group IIa phospholipase
A2. Arterioscler Thromb Vasc Biol 1999; 19:12841290.
144. Tietge UJ, Maugeais C, Lund-Katz S et al. Human secretory
phospholipase A2 mediates decreased plasma levels of HDL cholesterol and apoA-I
in response to inflammation in human apoA-I transgenic mice. Arterioscler
Thromb Vasc Biol 2002; 22:12131218.
145. Christensen EI, Birn H. Megalin and cubilin: multifunctional endocytic
receptors. Nat Rev Mol Cell Biol 2002; 3:256266.
146. Moestrup SK, Kozyraki R. Cubilin, a high-density lipoprotein receptor.
Curr Opin Lipidol 2000; 11:133140.
147. Kozyraki R, Fyfe J, Kristiansen M et al. The intrinsic factor-vitamin
B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating
endocytosis of high-density lipoprotein. Nat Med 1999; 5:656661.
148. Moestrup SK, Kozyraki R, Kristiansen M et al. The intrinsic
factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding
peripheral membrane protein with homology to developmental proteins. J
Biol Chem 1998; 273:52355242.
149. Hammad SM, Stefansson S, Twal WO et al. Cubilin, the endocytic
receptor for intrinsic factor-vitamin B(12) complex, mediates high-density
lipoprotein holoparticle endocytosis. Proc Natl Acad Sci USA 1999;
96:1015810163.
150. Curtiss LK, Boisvert WA. Apolipoprotein E and atherosclerosis. Curr
Opin Lipidol 2000; 11:243251.
151. Schneider WJ, Nimpf J. LDL receptor relatives at the crossroad of
endocytosis and signalling. Cell Mol Life Sci 2003; 60:892903.
152. Fidge NH. High density lipoprotein receptors, binding proteins, and
ligands. J Lipid Res 1999; 40:187201.
153. Kambouris AM, Roach PD, Calvert GD et al. Retroendocytosis
of high density lipoproteins by the human hepatoma cell line, HepG2. Arteriosclerosis
1990; 10:582590.
154. Silver DL, Wang N, Tall AR. Defective HDL particle uptake in ob/ob
hepatocytes causes decreased recycling, degradation, and selective lipid uptake.
J Clin Invest 2000; 105:151159.
155. Silver DL, Jiang XC, Tall AR. Increased high density lipoprotein
(HDL), defective hepatic catabolism of ApoA-I and ApoA-II, and decreased ApoA-I
mRNA in ob/ob mice. Possible role of leptin in stimulation of HDL turnover.
J Biol Chem 1999; 274:41404146.
156. Maron DJ. The epidemiology of low levels of high-density lipoprotein
cholesterol in patients with and without coronary artery disease. Am
J Cardiol 2000; 86:11L14L.
157. Young CE, Karas RH, Kuvin JT. High-density lipoprotein cholesterol
and coronary heart disease. Cardiol Rev 2004; 12:107119.
158. Assmann G. Pro and con: high-density lipoprotein, triglycerides,
and other lipid subfractions are the future of lipid management. Am
J Cardiol 2001; 87(Suppl 5A):2B7B.
159. Cullen P, Assmann G. High risk strategies for atherosclerosis. Clin
Chim Acta 1999; 286:3145.
160. Voss R, Cullen P, Schulte H et al. Prediction of risk of coronary
events in middle-aged men in the Prospective Cardiovascular Mόnster Study
(PROCAM) using neural networks. Int J Epidemiol 2002; 31:12531262.
161. Assmann G, Cullen P, Schulte H. The Mόnster Heart Study (PROCAM).
Results of follow-up at 8 years. Eur Heart J 1998; 19(Suppl
A):A211.
162. Cullen P, von Eckardstein A, Souris S et al. Dyslipidaemia
and cardiovascular risk in diabetes. Diabetes Obes Metab 1999;
1:189198.
163. Despres JP, Lemieux I, Dagenais GR et al. HDL-cholesterol
as a marker of coronary heart disease risk: the Quebec cardiovascular study.
Atherosclerosis 2000; 153:263272.
164. Assmann G, Nofer JR, Schulte H. Cardiovascular risk assessment in
metabolic syndrome: view from PROCAM. Endocrinol Metab Clin North Am
2004; 33:377392.
165. Barter P. Metabolic abnormalities: high-density lipoproteins. Endocrinol
Metab Clin North Am 2004; 33:393403.
166. Ridker PM, Glynn RJ, Hennekens CH. C-reactive protein adds to the
predictive value of total and HDL cholesterol in determining risk of first
myocardial infarction. Circulation 1998; 97:20072011.
167. Rifai N, Ridker PM. High-sensitivity C-reactive protein: a novel
and promising marker of coronary heart disease. Clin Chem 2001;
47:403411.
168. Jeppesen J, Hein HO, Suadicani P et al. Triglyceride concentration
and ischemic heart disease: an eight-year follow-up in the Copenhagen Male
Study. Circulation 1998; 97:10291036.
169. BIP Study Group. Secondary prevention by raising HDL cholesterol
and reducing triglycerides in patients with coronary heart disease: the Bezafibrate
Infarction Prevention (BIP) study. Circulation 2000; 102:2127.
170. Silverman DI, Ginsburg GS, Pasternak RC. High-density lipoprotein
subfractions. Am J Med 1993; 94:636645.
171. Wilson HM, Patel JC, Russell D et al. Alterations in the concentration
of an apolipoprotein E-containing subfraction of plasma high density lipoprotein
in coronary heart disease. Clin Chim Acta 1993; 220:175187.
172. Johansson J, Walldius G, Carlson LA. Close correlation between high-density
lipoprotein and triglycerides in normotriglyceridaemia. J Intern Med
1992; 232:4351.
173. Johansson J, Carlson LA, Landou C et al. High density lipoproteins
and coronary atherosclerosis. A strong inverse relation with the largest particles
is confined to normotriglyceridemic patients. Arterioscler Thromb 1991;
11:174182.
174. Kronenberg F, Stόhlinger M, Trenkwalder E et al. Low apolipoprotein
A-IV plasma concentrations in men with coronary artery disease. J Am
Coll Cardiol 2000; 36:751757.
175. Duriez P, Fruchart JC. High-density lipoprotein subclasses and apolipoprotein
A-I. Clin Chim Acta 1999; 286:97114.
176. Davignon J, Cohn JS, Mabile L et al. Apolipoprotein E and
atherosclerosis: insight from animal and human studies. Clin Chim Acta
1999; 286:115143.
177. Miller NE. Associations of high-density lipoprotein subclasses and
apolipoproteins with ischemic heart disease and coronary atherosclerosis.
Am Heart J 1987; 113:589597.
178. Luc G, Parra HJ, Zylberberg G et al. Plasma concentrations
of apolipoprotein A-I containing particles in normolipidaemic young men. Eur
J Clin Invest 1991; 21:118122.
179. Puchois P, Kandoussi A, Fievet P et al. Apolipoprotein A-I
containing lipoproteins in coronary artery disease. Atherosclerosis
1987; 68:3540.
180. Genest JJ Jr, Bard JM, Fruchart JC et al. Plasma apolipoprotein
A-I, A-II, B, E and C-III containing particles in men with premature coronary
artery disease. Atherosclerosis 1991; 90:149157.
181. Amouyel P, Isorez D, Bard JM et al. Parental history of early
myocardial infarction is associated with decreased levels of lipoparticle
AI in adolescents. Arterioscler Thromb 1993; 13:16401644.
182. Luc G, Bard JM, Lussier-Cacan S et al. High-density lipoprotein
particles in octogenarians. Metabolism 1991; 40:12381243.
183. Kalopissis AD, Chambaz J. Transgenic animals with altered high-density
lipoprotein composition and functions. Curr Opin Lipidol 2000;
11:149153.
184. Von Eckardstein A, Langer C, Engel Tet al. ATP binding cassette
transporter ABCA1 modulates the secretion of apolipoprotein E from human monocyte-derived
macrophages. FASEB J 2001; 15:15551561.
185. Rubin EM, Krauss RM, Spangler EA et al. Inhibition of early
atherogenesis in transgenic mice by human apolipoprotein AI. Nature
1991; 353:265267.
186. Swanson ME, Hughes TE, Denny IS et al. High level expression
of human apolipoprotein A-I in transgenic rats raises total serum high density
lipoprotein cholesterol and lowers rat apolipoprotein A-I. Transgenic
Res 1992; 1:142147.
187. Benoit P, Emmanuel F, Caillaud JM et al. Somatic gene transfer
of human ApoA-I inhibits atherosclerosis progression in mouse models. Circulation
1999; 99:105110.
188. Plump AS, Scott CJ, Breslow JL. Human apolipoprotein A-I gene expression
increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein
E-deficient mouse. Proc Natl Acad Sci USA 1994; 91:96079611.
189. Dansky HM, Charlton SA, Barlow CB et al. Apo A-I inhibits
foam cell formation in Apo E-deficient mice after monocyte adherence to endothelium.
J Clin Invest 1999; 104:3139.
190. Tangirala RK, Tsukamoto K, Chun SH et al. Regression of atherosclerosis
induced by liver-directed gene transfer of apolipoprotein A-I in mice. Circulation
1999; 100:18161822.
191. Liu AC, Lawn RM, Verstuyft JG et al. Human apolipoprotein
A-I prevents atherosclerosis associated with apolipoprotein[a] in transgenic
mice. J Lipid Res 1994; 35:22632267.
192. Li H, Reddick RL, Maeda N. Lack of apoA-I is not associated with
increased susceptibility to atherosclerosis in mice. Arterioscler Thromb
1993; 13:18141821.
193. Voyiaziakis E, Goldberg IJ, Plump AS et al. ApoA-I deficiency
causes both hypertriglyceridemia and increased atherosclerosis in human apoB
transgenic mice. J Lipid Res 1998; 39:313321.
194. Shah PK, Yano J, Reyes O et al. High-dose recombinant apolipoprotein
A-I(milano) mobilizes tissue cholesterol and rapidly reduces plaque lipid
and macrophage content in apolipoprotein E-deficient mice. Potential implications
for acute plaque stabilization. Circulation 2001; 103:30473050.
195. Shah PK, Nilsson J, Kaul S et al. Effects of recombinant apolipoprotein
A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice.
Circulation 1998; 97:780785.
196. Duverger N, Kruth H, Emmanuel F et al. Inhibition of atherosclerosis
development in cholesterol-fed human apolipoprotein A-I-transgenic rabbits.
Circulation 1996; 94:713717.
197. Warden CH, Hedrick CC, Qiao JH et al. Atherosclerosis in transgenic
mice overexpressing apolipoprotein A-II. Science 1993; 261:469472.
198. Escola-Gil JC, Marzal-Casacuberta A, Julve-Gil J et al. Human
apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in
transgenic mice at a level similar to that in humans: evidence of a potentially
relevant species-specific interaction with diet. J Lipid Res 1998;
39:457462.
199. Marzal-Casacuberta A, Blanco-Vaca F, Ishida BY et al. Functional
lecithin:cholesterol acyltransferase deficiency and high density lipoprotein
deficiency in transgenic mice overexpressing human apolipoprotein A-II. J
Biol Chem 1996; 271:67206728.
200. Schultz JR, Verstuyft JG, Gong EL et al. Protein composition
determines the anti-atherogenic properties of HDL in transgenic mice. Nature
1993; 365:762764.
201. Duverger N, Tremp G, Caillaud JM et al. Protection against
atherogenesis in mice mediated by human apolipoprotein A-IV. Science
1996; 273:966968.
202. Solajic-Bozicevic N, Stavjenic-Rukavina A, Sesto M. Lecithin-cholesterol
acyltransferase activity in patients with coronary artery disease examined
by coronary angiography. Clin Investig 1994; 72:951956.
203. Solajic-Bozicevic N, Stavljenic A, Sesto M. Lecithin:cholesterol
acyltransferase activity in patients with acute myocardial infarction and
coronary heart disease. Artery 1991; 18:326340.
204. Kuivenhoven JA, Pritchard H, Hill J et al. The molecular pathology
of lecithin:cholesterol acyltransferase (LCAT) deficiency syndromes. J
Lipid Res 1997; 38:191205.
205. Santamarina-Fojo S, Lambert G, Hoeg JM et al. Lecithin-cholesterolacyl
transferase: role in lipoprotein metabolism, reverse cholesterol transport
and atherosclerosis. Curr Opin Lipidol 2000; 11:267275.
206. Dobiasova M, Frohlich JJ. Advances in understanding of the role of
lecithin cholesterol acyltransferase (LCAT) in cholesterol transport. Clin
Chim Acta 1999; 286:257271.
207. Jonas A. Regulation of lecithin cholesterol acyltransferase activity.
Prog Lipid Res 1998; 37:209234.
208. Berard AM, Foger B, Remalev A et al. High plasma HDL concentrations
associated with enhanced atherosclerosis in transgenic mice overexpressing
lecithin-cholesteryl acyltransferase. Nat Med 1997; 3:744749.
209. Fφger B, Chase M, Amar MJ et al. Cholesteryl ester transfer
protein corrects dysfunctional high density lipoproteins and reduces aortic
atherosclerosis in lecithin cholesterol acyltransferase transgenic mice. J
Biol Chem 1999; 274:3691236920.
210. Hoeg JM, Santamarina-Fojo S, Berard AM et al. Overexpression
of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced
atherosclerosis. Proc Natl Acad Sci USA 1996; 93:1144811453.
211. Luo Y, Tall AR. Sterol upregulation of human CETP expression in vitro
and in transgenic mice by an LXR element. J Clin Invest 2000; 105:513520.
212. Christison JK, Rye KA, Stocker R. Exchange of oxidized cholesteryl
linoleate between LDL and HDL mediated by cholesteryl ester transfer protein.
J Lipid Res 1995; 36:20172026.
213. Nagano M, Yamashita S, Hirano K et al. Molecular mechanisms
of cholesteryl ester transfer protein deficiency in Japanese. J Atheroscler
Thromb 2004; 11:110121.
214. Inazu A, Koizumi J, Mabuchi H. Cholesteryl ester transfer protein
and atherosclerosis. Curr Opin Lipidol 2000; 11:389396.
215. Yamashita S, Sakai N, Hirano K et al. Molecular genetics of
plasma cholesteryl ester transfer protein. Curr Opin Lipidol 1997;
8:101110.
216. Zhong S, Sharp DS, Grove JS et al. Increased coronary heart
disease in Japanese-American men with mutation in the cholesteryl ester transfer
protein gene despite increased HDL levels. J Clin Invest 1996;
97:29172923.
217. Hirano K, Yamashita S, Nakajima N et al. Genetic cholesteryl
ester transfer protein deficiency is extremely frequent in the Omagari area
of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is
not associated with longevity. Arterioscler Thromb Vasc Biol 1997;
17:10531059.
218. Moriyama Y, Okamura T, Inazu A et al. A low prevalence of
coronary heart disease among subjects with increased high-density lipoprotein
cholesterol levels, including those with plasma cholesteryl ester transfer
protein deficiency. Prev Med 1998; 27:659667.
219. Bruce C, Sharp DS, Tall AR. Relationship of HDL and coronary heart
disease to a common amino acid polymorphism in the cholesteryl ester transfer
protein in men with and without hypertriglyceridemia. J Lipid Res 1998;
39:10711078.
220. Agerholm-Larsen B, Tybiaerg-Hansen A, Schnohr P et al. Common
cholesteryl ester transfer protein mutations, decreased HDL cholesterol, and
possible decreased risk of ischemic heart disease: the Copenhagen City Heart
Study. Circulation 2000; 102:21972203.
221. Ordovas JM, Cupples LA, Corella D et al. Association of cholesteryl
ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses
and coronary heart disease risk: the Framingham study. Arterioscler
Thromb Vasc Biol 2000; 20:13231329.
222. Freeman DJ, Samani NJ, Wilson V et al. A polymorphism of the
cholesteryl ester transfer protein gene predicts cardiovascular events in
non-smokers in the West of Scotland Coronary Prevention Study. Eur
Heart J 2003; 24:18331842.
223. Marotti KR, Castle CK, Boyle TP et al. Severe atherosclerosis
in transgenic mice expressing simian cholesteryl ester transfer protein. Nature
1993; 364:7375.
224. Herrera VL, Makrides SC, Xie HX et al. Spontaneous combined
hyperlipidemia, coronary heart disease and decreased survival in Dahl salt-sensitive
hypertensive rats transgenic for human cholesteryl ester transfer protein.
Nat Med 1999; 5:13831389.
225. Plump AS, Masucci-Magoulas L, Bruce C et al. Increased atherosclerosis
in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl
ester transfer protein transgene expression. Arterioscler Thromb Vasc
Biol 1999; 19:11051110.
226. Rittershaus CW, Miller DP, Thomas LJ et al. Vaccine-induced
antibodies inhibit CETP activity in vivo and reduce aortic lesions in a rabbit
model of atherosclerosis. Arterioscler Thromb Vasc Biol 2000; 20:21062112.
227. Sugano M, Makino N, Sawada S et al. Effect of antisense oligonucleotides
against cholesteryl ester transfer protein on the development of atherosclerosis
in cholesterol-fed rabbits. J Biol Chem 1998; 273:50335036.
228. Okamoto H, Yonemori F, Wakitani K et al. A cholesteryl ester
transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature
2000; 406:203207.
229. Zhang B, Fan P, Shimoji E et al. Inhibition of cholesteryl
ester transfer protein activity by JTT-705 increases apolipoprotein E-containing
high-density lipoprotein and favorably affects the function and enzyme composition
of high-density lipoprotein in rabbits. Arterioscler Thromb Vasc Biol
2004; 24:19101915.
230. De Grooth GJ, Kuivenhoven JA, Stalenhoef AFH et al. Efficacy
and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705,
in humans: a randomized phase II dose-response study. Circulation 2002;
105:21592165.
231. Clark RW, Sutfin TA, Ruggeri RB et al. Raising high-density
lipoprotein in humans through inhibition of cholesteryl ester transfer protein:
an initial multidose study of torcetrapib. Arterioscler Thromb Vasc
Biol 2004; 24:490497.
232. Schlitt A, Bickel C, Thumma P et al. High plasma phospholipid
transfer protein levels as a risk factor for coronary artery disease. Arterioscler
Thromb Vasc Biol 2003; 23:18571862.
233. van Haperen R, van Tol A, van Gent T et al. Increased risk
of atherosclerosis by elevated plasma levels of phospholipid transfer protein.
J Biol Chem 2002; 277:4893848943.
234. Cheung MC, Wolfbauer G, Kennedy H et al. Plasma phospholipid
transfer protein activity in patients with low HDL and cardiovascular disease
treated with simvastatin and niacin. Biochim Biophys Acta 2001;
1537:117124.
235. Desrumaux C, Athias A, Bessede G et al. Mass concentration
of plasma phospholipid transfer protein in normolipidemic type IIa hyperlipidemic,
type IIb hyperlipidemic, and non-insulin-dependent diabetic subjects as measured
by a specific ELISA. Arterioscler Thromb Vasc Biol 1999; 19:266275.
236. Murdoch SJ, Carr MC, Hokanson JE et al. PLTP activity in premenopausal
women. Relationship with lipoprotein lipase, HDL, LDL, body fat, and insulin
resistance. J Lipid Res 2000; 41:237244.
237. Jiang XC, Tall AR, Qin S et al. Phospholipid transfer protein
deficiency protects circulating lipoproteins from oxidation due to the enhanced
accumulation of vitamin E. J Biol Chem 2002; 277:3185031856.
238. Jiang XC, Qin S, Qiao C et al. Apolipoprotein B secretion
and atherosclerosis are decreased in mice with phospholipid-transfer protein
deficiency. Nat Med 2001; 7:847852.
239. Yang XP, Yan D, Qiao C et al. Increased atherosclerotic lesions
in apoE mice with plasma phospholipid transfer protein overexpression. Arterioscler
Thromb Vasc Biol 2003; 23:16011607.
240. Tall A. Plasma lipid transfer proteins. Annu Rev Biochem 1995;
64:235257.
241. Huuskonen J, Ehnholm C. Phospholipid transfer protein in lipid metabolism.
Curr Opin Lipidol 2000; 11:285289.
242. Dugi KA, Brandauer K, Schmidt N et al. Low hepatic lipase
activity is a novel risk factor for coronary artery disease. Circulation
2001; 104:30573062.
243. Dugi KA, Feuerstein IM, Hill S et al. Lipoprotein lipase correlates
positively and hepatic lipase inversely with calcific atherosclerosis in homozygous
familial hypercholesterolemia. Arterioscler Thromb Vasc Biol 1997;
17:354364.
244. Barth JD, Jansen H, Kromhout D et al. Progression and regression
of human coronary atherosclerosis. The role of lipoproteins, lipases and thyroid
hormones in coronary lesion growth. Atherosclerosis 1987; 68:5158.
245. Connelly PW, Hegele RA. Hepatic lipase deficiency. Crit Rev
Clin Lab Sci 1998; 35:547572.
246. Hokanson JE, Cheng S, Snell-Bergeon JK et al. A common promoter
polymorphism in the hepatic lipase gene (LIPC-480C>T) is associated with
an increase in coronary calcification in type 1 diabetes. Diabetes
2002; 51:12081213.
247. Shohet RV, Vega GL, Anwar A et al. Hepatic lipase (LIPIC)
promoter polymorphism in men with coronary artery disease. Allele frequency
and effects on hepatic lipase activity and plasma HDL-C concentrations. Arterioscler
Thromb Vasc Biol 1999; 19:19751978.
248. Jansen H, Verhoeven AJ, Weeks L et al. Common C-to-T substitution
at position–480 of the hepatic lipase promoter associated with a lowered
lipase activity in coronary artery disease patients. Arterioscler Thromb
Vasc Biol 1997; 17:28372842.
249. Mezdour H, Jones R, Dengremont C et al. Hepatic lipase deficiency
increases plasma cholesterol but reduces susceptibility to atherosclerosis
in apolipoprotein E-deficient mice. J Biol Chem 1997; 272:1357013575.
250. Busch SJ, Barnhart RL, Martin GA et al. Human hepatic triglyceride
lipase expression reduces high density lipoprotein and aortic cholesterol
in cholesterol-fed transgenic mice. J Biol Chem 1994; 269:1637616382.
251. Deeb SS, Zambon A, Carr MC et al. Hepatic lipase and dyslipidemia:
interactions among genetic variants, obesity, gender, and diet. J Lipid
Res 2003; 44:12791286.
252. Thuren T. Hepatic lipase and HDL metabolism. Curr Opin Lipidol
2000; 11:277283.
253. Schiering A, Menschikowski M, Mueller E et al. Analysis of
secretory group II phospholipase A2 expression in human aortic tissue in dependence
on the degree of atherosclerosis. Atherosclerosis 1999; 144:7378.
254. Elinder LS, Dumitrescu A, Larsson P et al. Expression of phospholipase
A2 isoforms in human normal and atherosclerotic arterial wall. Arterioscler
Thromb Vasc Biol 1997; 17:22572263.
255. Liu PY, Li YH, Tsai WC et al. Prognostic value and the changes
of plasma levels of secretory type II phospholipase A2 in patients with coronary
artery disease undergoing percutaneous coronary intervention. Eur Heart
J 2003; 24:18241832.
256. Kugiyama K, Ota Y, Sugiyama S et al. Prognostic value of plasma
levels of secretory type II phospholipase A2 in patients with unstable angina
pectoris. Am J Cardiol 2000; 86:718722.
257. Murakami M, Kudo I. New phospholipase A(2) isozymes with a potential
role in atherosclerosis. Curr Opin Lipidol 2003; 14:431436.
258. Kozarsky KF, Donahee MH, Glick JM et al. Gene transfer and
hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in
the cholesterol-fed LDL receptor-deficient mouse. Arterioscler Thromb
Vasc Biol 2000; 20:721727.
259. Ueda Y, Gong E, Royer L et al. Relationship between expression
levels and atherogenesis in scavenger receptor class B, type I transgenics.
J Biol Chem 2000; 275:2036820373.
260. Arai T, Wang N, Bezouevski M et al. Decreased atherosclerosis
in heterozygous low density lipoprotein receptor-deficient mice expressing
the scavenger receptor BI transgene. J Biol Chem 1999; 274:23662371.
261. Huszar D, Varban ML, Rinninger F et al. Increased LDL cholesterol
and atherosclerosis in LDL receptor-deficient mice with attenuated expression
of scavenger receptor B1. Arterioscler Thromb Vasc Biol 2000; 20:10681073.
262. Braun A, Trigatti BL, Post MJ et al. Loss of SR-BI expression
leads to the early onset of occlusive atherosclerotic coronary artery disease,
spontaneous myocardial infarctions, severe cardiac dysfunction, and premature
death in apolipoprotein E-deficient mice. Circ Res 2002; 90:270276.
263. Zhang W, Yancey PG, Su YR et al. Inactivation of macrophage
scavenger receptor class B type I promotes atherosclerotic lesion development
in apolipoprotein E-deficient mice. Circulation 2003; 108:22582263.
264. Hsu LA, Ko YL, Wu S et al. Association between a novel 11-base
pair deletion mutation in the promoter region of the scavenger receptor class
B type I gene and plasma HDL cholesterol levels in Taiwanese Chinese. Arterioscler
Thromb Vasc Biol 2003; 23:18691874.
265. Liscum L, Munn NJ. Intracellular cholesterol transport. Biochim
Biophys Acta 1999; 1438:1937.
266. Fielding CJ, Fielding PE. Intracellular cholesterol transport. J
Lipid Res 1997; 38:15031521.
267. Dietschy JM, Turley SD, Spady DK. Role of liver in the maintenance
of cholesterol and low density lipoprotein homeostasis in different animal
species, including humans. J Lipid Res 1993; 34:16371659.
268. Glomset JA. The plasma lecithins:cholesterol acyltransferase reaction.
J Lipid Res 1968; 9:155167.
269. von Eckardstein A, Nofer JR, Assmann G. High density lipoproteins
and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport.
Arterioscler Thromb Vasc Biol 2001; 21:1327.
270. Rader DJ. Regulation of reverse cholesterol transport and clinical
implications. Am J Cardiol 2003; 92:42J49J.
271. Sviridov D, Nestel P. Dynamics of reverse cholesterol transport:
protection against atherosclerosis. Atherosclerosis 2002; 161:245254.
272. Maxfield FR, Wustner D. Intracellular cholesterol transport. J
Clin Invest 2002; 110:891898.
273. Soccio RE, Breslow JL. Intracellular cholesterol transport. Arterioscler
Thromb Vasc Biol 2004; 24:11501160.
274. Yancey PG, Bortnick AE, Kellner-Weibel G et al. Importance
of different pathways of cellular cholesterol efflux. Arterioscler
Thromb Vasc Biol 2003; 23:712719.
275. Rothblat GH, de la Llera-Moya M, Atger V et al. Cell cholesterol
efflux: integration of old and new observations provides new insights. J
Lipid Res 1999; 40:781796.
276. Fielding CJ, Fielding PE. Cellular cholesterol efflux. Biochim
Biophys Acta 2001; 1533:175189.
277. Yokoyama S. Release of cellular cholesterol: molecular mechanism
for cholesterol homeostasis in cells and in the body. Biochim Biophys
Acta 2000; 1529:231244.
278. Jones PM, George AM. The ABC transporter structure and mechanism:
perspectives on recent research. Cell Mol Life Sci 2004; 61:682699.
279. Borst P, Elferink RO. Mammalian ABC transporters in health and disease.
Annu Rev Biochem 2002; 71:537592.
280. Dean M, Hamon Y, Chimini G et al. The human ATP-binding cassette
(ABC) transporter superfamily. J Lipid Res 2001; 42:10071017.
281. Hamon Y, Broccardo C, Chambenoit O et al. ABC1 promotes engulfment
of apoptotic cells and transbilayer redistribution of phosphatidylserine.
Nat Cell Biol 2000; 2:399406.
282. Hamon Y, Luciani MF, Becq F et al. Interleukin-1beta secretion
is impaired by inhibitors of the ATP binding cassette transporter, ABC1. Blood
1997; 90:29112915.
283. Fitzgerald ML, Morris AL, Chroni A et al. ABCA1 and amphipathic
apolipoproteins form high-affinity molecular complexes required for cholesterol
efflux. J Lipid Res 2004; 45:287294.
284. Fitzgerald ML, Morris AL, Rhee JS et al. Naturally occurring
mutations in the largest extracellular loops of ABCA1 can disrupt its direct
interaction with apolipoprotein A-I. J Biol Chem 2002; 277:3317833187.
285. Chroni A, Liu T, Fitzgerald ML et al. Cross-linking and lipid
efflux properties of apoA-I mutants suggest direct association between apoA-I
helices and ABCA1. Biochemistry 2004; 43:21262139.
286. Drobnik W, Borsukova H, Bottcher A et al. Apo AI/ANCA1-dependent
and HDL3-mediated lipid efflux from compositionally distinct cholesterol-based
microdomains. Traffic 2002; 3:268278.
287. Marguet D, Chimini G. The ABCA1 transporter and ApoA-I: obligate
or facultative partners? Trends Cardiovasc Med 2002; 12:294298.
288. Mendez AJ, Lin G, Wade DP et al. Membrane lipid domains distinct
from cholesterol/sphingomyelin-rich rafts are involved in the ABCA1-mediated
lipid secretory pathway. J Biol Chem 2001; 276:31583166.
289. Chambenoit O, Hamon Y, Marguet D et al. Specific docking of
apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter.
J Biol Chem 2001; 276:99559960.
290. Wang N, Silver DL, Thiele C et al. ATP-binding cassette transporter
A1 (ABCA1) functions as a cholesterol efflux regulatory protein. J
Biol Chem 2001; 276:2374223747.
291. Tang C, Vaughan AM, Oram JF. Janus kinase 2 modulates the apolipoprotein
interactions with ABCA1 required for removing cellular cholesterol. J
Biol Chem 2004; 279:76227628.
292. Yamauchi Y, Hayashi M, Abe-Dohmae S et al. Apolipoprotein
A-I activates protein kinase C alpha signaling to phosphorylate and stabilize
ATP binding cassette transporter A1 for the high density lipoprotein assembly.
J Biol Chem 2003; 278:4789047897.
293. Haidar B, Denis M, Krimbou L et al. cAMP induces ABCA1 phosphorylation
activity and promotes cholesterol efflux from fibroblasts. J Lipid
Res 2002; 43:20872094.
294. Wang N, Silver DL, Costet P et al. Specific binding of ApoA-I,
enhanced cholesterol efflux, and altered plasma membrane morphology in cells
expressing ABC1. J Biol Chem 2000; 275:3305333058.
295. Munehira Y, Ohnishi T, Kawamoto S et al. Alpha1-syntrophin
modulates turnover of ABCA1. J Biol Chem 2004; 279:1590115095.
296. Neufeld EB, Stonik JA, Demosky SJ Jr et al. The ABCA1 transporter
modulates late endocytic trafficking: insights from the correction of the
genetic defect in Tangier disease. J Biol Chem 2004; 279:1557115578.
297. Neufeld EB, Remaley AT, Demosky SJ et al. Cellular localization
and trafficking of the human ABCA1 transporter. J Biol Chem 2001;
276:2758427590.
298. Tsukamoto K, Hirano K, Tsujii K et al. ATP-binding cassette
transporter-1 induces rearrangement of actin cytoskeletons possibly through
Cdc42/N-WASP. Biochem Biophys Res Commun 2001; 287:757765.
299. Zhou X, Engel T, Goepfert C et al. The ATP binding cassette
transporter A1 contributes to the secretion of interleukin 1beta from macrophages
but not from monocytes. Biochem Biophys Res Commun 2002; 291:598604.
300. Tontonoz P, Mangelsdorf DJ. Liver X receptor signaling pathways in
cardiovascular disease. Mol Endocrinol 2003; 17:985993.
301. Costet P, Lalanne F, Gerbod-Giannone MC et al. Retinoic acid
receptor-mediated induction of ABCA1 in macrophages. Mol Cell Biol
2003; 23:77567766.
302. Laffitte BA, Repa JJ, Joseph SB et al. LXRs control lipid-inducible
expression of the apolipoprotein E gene in macrophages and adipocytes. Proc
Natl Acad Sci USA 2001; 98:507512.
303. Venkateswaran A, Laffitte BA, Joseph SB et al. Control of
cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. Proc
Natl Acad Sci USA 2000; 97:1209712102.
304. Wang Y, Oram JF. Unsaturated fatty acids inhibit cholesterol efflux
from macrophages by increasing degradation of ATP-binding cassette transporter
A1. J Biol Chem 2002; 277:56925697.
305. Uehara Y, Engel T, Li Z et al. Polyunsaturated fatty acids
and acetoacetate downregulate the expression of the ATP-binding cassette transporter
A1. Diabetes 2002; 51:29222928.
306. Castrillo A, Joseph SB, Vaidya SA et al. Crosstalk between
LXR and toll-like receptor signaling mediates bacterial and viral antagonisms
of cholesterol metabolism. Mol Cell 2003; 12:805816.
307. Baranova I, Vishnyakova T, Bocharov A et al. Lipopolysaccharide
down regulates both scavenger receptor BI and ATP binding cassette transporter
AI in RAW cells. Infect Immun 2002; 70:29953003.
308. Wang XQ, Panousis CG, Alfaro ML et al. Interferon-gamma-mediated
downregulation of cholesterol efflux and ABC1 expression is by the Stat1 pathway.
Arterioscler Thromb Vasc Biol 2002; 22:e59.
309. Witting SR, Maiorano JN, Davidson WS. Ceramide enhances cholesterol
efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding
cassette transporter A1. J Biol Chem 2003; 278:4012140127.
310. Wang N, Chen W, Linsel-Nitschke P et al. A PEST sequence in
ABCA1 regulates degradation by calpain protease and stabilization of ABCA1
by apoA-I. J Clin Invest 2003; 111:99107.
311. Martinez LO, Agerholm-Larsen B, Wang N et al. Phosphorylation
of a pest sequence in ABCA1 promotes calpain degradation and is reversed by
ApoA-I. J Biol Chem 2003; 278:3736837374.
312. Abe-Dohmae S, Ikeda Y, Matsuo M et al. Human ABCA7 supports
apolipoprotein-mediated release of cellular cholesterol and phospholipid to
generate high density lipoprotein. J Biol Chem 2004; 279:604611.
313. Wang N, Lan D, Gerbod-Giannone M et al. ATP-binding cassette
transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid
but not cholesterol efflux. J Biol Chem 2003; 278:4290642912.
314. Wang N, Lan D, Chen W et al. ATP-binding cassette transporters
G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.
Proc Natl Acad Sci USA 2004; 101:97749779.
315. Aiello RJ, Brees D, Bourassa PA et al. Increased atherosclerosis
in hyperlipidemic mice with inactivation of ABCA1 in macrophages. Arterioscler
Thromb Vasc Biol 2002; 22:630637.
316. McNeish J, Aiello RJ, Guyot D et al. High density lipoprotein
deficiency and foam cell accumulation in mice with targeted disruption of
ATP-binding cassette transporter-1. Proc Natl Acad Sci USA 2000;
97:42454250.
317. van Eck M, Bos IS, Kaminski WE et al. Leukocyte ABCA1 controls
susceptibility to atherosclerosis and macrophage recruitment into tissues.
Proc Natl Acad Sci USA 2002; 99:62986303.
318. Haghpassand M, Bourassa PA, Francone OL et al. Monocyte/macrophage
expression of ABCA1 has minimal contribution to plasma HDL levels. J
Clin Invest 2001; 108:13151320.
319. Wellington CL, Brunham LR, Zhou S et al. Alterations of plasma
lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1.
J Lipid Res 2003; 44:14701480.
320. Vaisman BL, Lambert G, Amar M et al. ABCA1 overexpression
leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion
in transgenic mice. J Clin Invest 2001; 108:303309.
321. Joyce CW, Amar MJ, Lambert G et al. The ATP binding cassette
transporter A1 (ABCA1) modulates the development of aortic atherosclerosis
in C57BL/6 and apoE-knockout mice. Proc Natl Acad Sci USA 2002;
99:407412.
322. Joseph SB, McKikkigin E, Pei L et al. Synthetic LXR ligand
inhibits the development of atherosclerosis in mice. Proc Natl Acad
Sci USA 2002; 99:76047609.
323. Tangirala RK, Bischoff ED, Joseph SB et al. Identification
of macrophage liver X receptors as inhibitors of atherosclerosis. Proc
Natl Acad Sci USA 2002; 99:1189611901.
324. Kuivenhoven JA, Hovingh GK, van Tol A et al. Heterozygosity
for ABCA1 gene mutations: effects on enzymes, apolipoproteins and lipoprotein
particle size. Atherosclerosis 2003; 171:311319.
325. Singaraja RR, Brunham LR, Visscher H et al. Efflux and atherosclerosis:
the clinical and biochemical impact of variations in the ABCA1 gene. Arterioscler
Thromb Vasc Biol 2003; 23:13221332.
326. van Dam MJ, de Groot E, Clee SM et al. Association between
increased arterial-wall thickness and impairment in ABCA1-driven cholesterol
efflux: an observational study. Lancet 2002; 359:3742.
327. Clee SM, Kastelein JJ, van Dam M et al. Age and residual cholesterol
efflux levels and coronary artery disease in ABCA1 heterozygotes. J
Clin Invest 2000; 106:12631270.
328. Linton MF, Atkinson JB, Fazio S. Prevention of atherosclerosis in
apolipoprotein E-deficient mice by bone marrow transplantation. Science
1995; 267:10341037.
329. Boisvert WA, Spangenberg J, Curtiss LK. Treatment of severe hypercholesterolemia
in apolipoprotein E-deficient mice by bone marrow transplantation. J
Clin Invest 1995; 96:11181124
330. Bellosta S, Mahley RW, Sanan DA et al. Macrophage-specific
expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic
apolipoprotein E-null mice. J Clin Invest 1995; 96:21702179.
331. Fazio S, Babaev VR, Murray AB et al. Increased atherosclerosis
in mice reconstituted with apolipoprotein E null macrophages. Proc
Natl Acad Sci USA 1997; 94:46474652.
332. Fazio S, Linton MF, Swift LL. The cell biology and physiologic relevance
of ApoE recycling. Trends Cardiovasc Med 2000; 10:2330.
333. Swertfeger DK, Bu G, Hui DY. Low density lipoprotein receptor-related
protein mediates apolipoprotein E inhibition of smooth muscle cell migration.
J Biol Chem 2002; 277:41414146.
334. Ishigami M, Swertfeger DK, Hui MS et al. Apolipoprotein E
inhibition of vascular smooth muscle cell proliferation but not inhibition
of migration is mediated through activation of inducible nitric oxide synthase.
Arterioscler Thromb Vasc Biol 2000; 20:10201026.
335. Stannard AK, Riddell DR, Sacre SM et al. Cell-derived apolipoprotein
E (ApoE) particles inhibit vascular cell adhesion molecule-1 (VCAM-1) expression
in human endothelial cells. J Biol Chem 2001; 276:4601146016.
336. Riddell DR, Graham A, Owen JS. Apolipoprotein E inhibits platelet
aggregation through the L-arginine:nitric oxide pathway. Implications for
vascular disease. J Biol Chem 1997; 272:8995.
337. Mazzone T. Apolipoprotein E secretion by macrophages: its potential
physiological functions. Curr Opin Lipidol 1996; 7:303307.
338. Fournier N, Atger V, Paul JL et al. Human ApoA-IV overexpression
in transgenic mice induces cAMP-stimulated cholesterol efflux from J774 macrophages
to whole serum. Arterioscler Thromb Vasc Biol 2000; 20:12831292.
339. Steinmetz A, Barbaras R, Ghalim N et al. Human apolipoprotein
A-IV binds to apolipoprotein A-I/A-II receptor sites and promotes cholesterol
efflux from adipose cells. J Biol Chem 1990; 265:78597863.
340. Duverger N, Ghalim N, Theret N et al. Lipoproteins containing
apolipoprotein A-IV: composition and relation to cholesterol esterification.
Biochim Biophys Acta 1994; 1211:2328.
341. Nofer JR, Kehrel B, Fobker M et al. HDL and arteriosclerosis:
beyond reverse cholesterol transport. Atherosclerosis 2002; 161:116.
342. Cockerill GW, Saklatvala J, Ridley SH et al. High-density
lipoproteins differentially modulate cytokine-induced expression of E-selectin
and cyclooxygenase-2. Arterioscler Thromb Vasc Biol 1999; 19:910917.
343. Endemann DH, Schiffrin EL. Endothelial dysfunction. J Am Soc
Nephrol 2004; 15:19831992.
344. Landmesser U, Hornig B, Drexler H. Endothelial dysfunction in hypercholesterolemia:
mechanisms, pathophysiological importance, and therapeutic interventions.
Semin Thromb Hemost 2000; 26:529537.
345. Shimokawa H. Primary endothelial dysfunction: atherosclerosis. J
Mol Cell Cardiol 1999; 31:2337.
346. Toikka JO, Ahotupa M, Viikari JS et al. Constantly low HDL-cholesterol
concentration relates to endothelial dysfunction and increased in vivo LDL-oxidation
in healthy young men. Atherosclerosis 1999; 147:133138.
347. Sattar N, Petrie JR, Jaap AJ. The atherogenic lipoprotein phenotype
and vascular endothelial dysfunction. Atherosclerosis 1998; 138:229235.
348. Kuvin JT, Patel AR, Sidhu M et al. Relation between high-density
lipoprotein cholesterol and peripheral vasomotor function. Am J Cardiol
2003; 92:275279.
349. Kuvin JT, Ramet ME, Patel AR et al. A novel mechanism for
the beneficial vascular effects of high-density lipoprotein cholesterol: enhanced
vasorelaxation and increased endothelial nitric oxide synthase expression.
Am Heart J 2002; 144:165172.
350. Lupattelli G, Marchesi S, Roscini AR et al. Direct association
between high-density lipoprotein cholesterol and endothelial function in hyperlipidemia.
Am J Cardiol 2002; 90:648650.
351. Li XP, Zhao SP, Zhang XY et al. Protective effect of high
density lipoprotein on endothelium-dependent vasodilatation. Int J
Cardiol 2000; 73:231236.
352. Kaufmann PA, Gnecchi-Ruscone T, Schafers KP et al. Low density
lipoprotein cholesterol and coronary microvascular dysfunction in hypercholesterolemia.
J Am Coll Cardiol 2000; 36:103109.
353. Matsuda Y, Hirata K, Inoue N et al. High density lipoprotein
reverses inhibitory effect of oxidized low density lipoprotein on endothelium-dependent
arterial relaxation. Circ Res 1993; 72:11031109.
354. Ota Y, Kugiyama K, Sugiyama S et al. Complexes of apoA-1 with
phosphatidylcholine suppress dysregulation of arterial tone by oxidized LDL.
Am J Physiol 1997; 273:H12151222.
355. Kuhn FE, Mohler ER, Satler LF et al. Effects of high-density
lipoprotein on acetylcholine-induced coronary vasoreactivity. Am J
Cardiol 1991; 68:14251430.
356. Bisoendial RJ, Hovingh GK, Levels JH et al. Restoration of
endothelial function by increasing high-density lipoprotein in subjects with
isolated low high-density lipoprotein. Circulation 2003; 107:29442948.
357. Spieker LE, Sudano I, Hurlimann D et al. High-density lipoprotein
restores endothelial function in hypercholesterolemic men. Circulation
2002; 105:13991402.
358. Yuhanna IS, Zhu Y, Cox BE et al. High-density lipoprotein
binding to scavenger receptor-BI activates endothelial nitric oxide synthase.
Nat Med 2001; 7:853857.
359. Mineo C, Yuhanna IS, Quon MJ et al. High density lipoprotein-induced
endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinase.
J Biol Chem 2003; 278:91429149.
360. Li XA, Titlow WB, Jackson BA et al. High density lipoprotein
binding to scavenger receptor, class B, type I activates endothelial nitric-oxide
synthase in a ceramide-dependent manner. J Biol Chem 2002; 277:1105811063.
361. Nofer JR, Hermingshaus G, Brodde M et al. Impaired platelet
activation in familial high density lipoprotein deficiency (Tangier disease).
J Biol Chem 2004; 279:3403234037.
362. Tamagaki T, Sawada S, Imamura H et al. Effects of high-density
lipoproteins on intracellular pH and proliferation of human vascular endothelial
cells. Atherosclerosis 1996; 123:7382.
363. Nofer JR, Levkau B, Wolinska I et al. Suppression of endothelial
cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids.
J Biol Chem 2001; 276:3448034485.
364. Sugano M, Tsuchida K, Makino N. High-density lipoproteins protect
endothelial cells from tumor necrosis factor-alpha-induced apoptosis. Biochem
Biophys Res Commun 2000; 272:872876.
365. Suc I, Escargueil-Blanc I, Troly M et al. HDL and ApoA prevent
cell death of endothelial cells induced by oxidized LDL. Arterioscler
Thromb Vasc Biol 1997; 17:21582166.
366. Packman CH, Rosenfeld SI, Leddy JP. High-density lipoprotein and
its apolipoproteins inhibit cytolytic activity of complement. Studies on the
nature of inhibitory moiety. Biochim Biophys Acta 1985; 812:107115.
367. Rosenfeld SI, Packman CH, Leddy JP. Inhibition of the lytic action
of cell-bound terminal complement components by human high density lipoproteins
and apoproteins. J Clin Invest 1983; 71:795808.
368. Pasqui AL, Bova G, Puccetti L et al. Complement activation
in hypercholesterolemia. Nutr Metab Cardiovasc Dis 2000; 10:137142.
369. Hamilton KK, Zhao J, Sims PJ. Interaction between apolipoproteins
A-I and A-II and the membrane attack complex of complement. Affinity of the
apoproteins for polymeric C9. J Biol Chem 1993; 268:36323638.
370. Vakeva A, Jauhiainen M, Ehnholm C et al. High-density lipoproteins
can act as carriers of glycophosphoinositol lipid-anchored CD59 in human plasma.
Immunology 1994; 82:2833.
371. Schmiedt W, Kinscherf R, Deigner HP et al. Complement C6 deficiency
protects against diet-induced atherosclerosis in rabbits. Arterioscler
Thromb Vasc Biol 1998; 18:17901795.
372. Fleisher LN, Tall AR, Witte LD et al. Stimulation of arterial
endothelial cell prostacyclin synthesis by high density lipoproteins. J
Biol Chem 1982; 257:66536655.
373. Cockerill GW, Reed S. High-density lipoprotein: multipotent effects
on cells of the vasculature. Int Rev Cytol 1999; 188:257297.
374. Vinals M, Martinez-Gonzalez J, Badimon L. Regulatory effects of HDL
on smooth muscle cell prostacyclin release. Arterioscler Thromb Vasc
Biol 1999; 19:24052411.
375. Vinals M, Martinez-Gonzalez J, Badimon JJ et al. HDL-induced
prostacyclin release in smooth muscle cells is dependent on cyclooxygenase-2
(Cox-2). Arterioscler Thromb Vasc Biol 1997; 17:34813488.
376. Unoki H, Fan J, Watanabe T. Low-density lipoproteins modulate endothelial
cells to secrete endothelin-1 in a polarized pattern: a study using a culture
model system simulating arterial intima. Cell Tissue Res 1999;
295:8999.
377. Tsai AL, Hsu MJ, Patsch W et al. Regulation of PGI2 activity
by serum proteins: serum albumin but not high density lipoprotein is the PGI2
binding and stabilizing protein in human blood. Biochim Biophys Acta
1991; 1115:131140.
378. Aoyama T, Yui Y, Morishita H et al. Prostaglandin I2 half-life
regulated by high density lipoprotein is decreased in acute myocardial infarction
and unstable angina pectoris. Circulation 1990; 81:17841791.
379. Kume N, Cybulsky MI, Gimbrone MA. Lysophosphatidylcholine, a component
of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules
in cultured human and rabbit arterial endothelial cells. J Clin Invest
1992; 90:11381144.
380. Navab M, Imes SS, Hama SY et al. Monocyte transmigration induced
by modification of low density lipoprotein in cocultures of human aortic wall
cells is due to induction of monocyte chemotactic protein 1 synthesis and
is abolished by high density lipoprotein. J Clin Invest 1991; 88:20392046.
381. Ashby DT, Rye KA, Clay MA et al. Factors influencing the ability
of HDL to inhibit expression of vascular cell adhesion molecule-1 in endothelial
cells. Arterioscler Thromb Vasc Biol 1998; 18:1450455.
382. Calabresi L, Franceschini G, Sirtori CR et al. Inhibition
of VCAM-1 expression in endothelial cells by reconstituted high density lipoproteins.
Biochem Biophys Res Commun 1997; 238:6165.
383. Cockerill GW, Rye KA, Gamble JR et al. High-density lipoproteins
inhibit cytokine-induced expression of endothelial cell adhesion molecules.
Arterioscler Thromb Vasc Biol 1995; 15:19871994.
384. Xia P, Vadas MA, Rye KA et al. High density lipoproteins (HDL)
interrupt the sphingosine kinase signaling pathway. A possible mechanism for
protection against atherosclerosis by HDL. J Biol Chem 1999; 274:3314333147.
385. Cockerill GW, McDonald MC, Mota-Filipe H et al. High density
lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic
shock. FASEB J 2001; 15:19411952.
386. Cockerill GW, Huehns TY, Weerasinghe A et al. Elevation of
plasma high-density lipoprotein concentration reduces interleukin-1-induced
expression of E-selectin in an in vivo model of acute inflammation. Circulation
2001; 103:108112.
387. Theilmeier G, Dr Geest B, Van Veldhoven PP et al. HDL-associated
PAF-AH reduces endothelial adhesiveness in apoE-/- mice. FASEB J 2000;
14:20322039.
388. Dimayuga P, Zhu J, Oguchi S et al. Reconstituted HDL containing
human apolipoprotein A-1 reduces VCAM-1 expression and neointima formation
following periadventitial cuff-induced carotid injury in apoE null mice. Biochem
Biophys Res Commun 1999; 264:465468.
389. Meade TW, Ruddock V, Stirling Y et al. Fibrinolytic activity,
clotting factors, and long-term incidence of ischaemic heart disease in the
Northwick Park Heart Study. Lancet 1993; 342:10761079.
390. Lowe GD, Yarnell JW, Sweetnam PM et al. Fibrin D-dimer, tissue
plasminogen activator, plasminogen activator inhibitor, and the risk of major
ischaemic heart disease in the Caerphilly Study. Thromb Haemost 1998;
79:129133.
391. Kaneko T, Wada H, Wakita Y et al. Enhanced tissue factor activity
and plasminogen activator inhibitor-1 antigen in human umbilical vein endothelial
cells incubated with lipoproteins. Blood Coagul Fibrinolysis 1994;
5:385392.
392. Rosenson RS, Lowe GD. Effects of lipids and lipoproteins on thrombosis
and rheology. Atherosclerosis 1998; 140:271280.
393. Carson SD. Plasma high density lipoproteins inhibit the activation
of coagulation factor X by factor VIIa and tissue factor. FEBS Lett
1981; 132:3740.
394. Epand RM, Stafford A, Leon B et al. HDL and apolipoprotein
A-I protect erythrocytes against the generation of procoagulant activity.
Arterioscler Thromb 1994; 14:17751783.
395. Griffin JH, Kojima K, Banka CL et al. High-density lipoprotein
enhancement of anticoagulant activities of plasma protein S and activated
protein C. J Clin Invest 1999; 103:219227.
396. Naqvi TZ, Shah PK, Ivey PA et al. Evidence that high-density
lipoprotein cholesterol is an independent predictor of acute platelet-dependent
thrombus formation. Am J Cardiol 1999; 84:10111017.
397. Nofer JR, Walter M, Kehrel B. HDL3-mediated inhibition of thrombin-induced
platelet aggregation and fibrinogen binding occurs via decreased production
of phosphoinositide-derived second messengers 1,2-diacylglycerol and inositol
1,4,5-tris-phosphate. Arterioscler Thromb Vasc Biol 1998; 18:861869.
398. Aviram M, Brook JG. Platelet interaction with high and low density
lipoproteins. Atherosclerosis 1983; 46:259268.
399. Li D, Weng S, Yang B et al. Inhibition of arterial thrombus
formation by ApoA1 Milano. Arterioscler Thromb Vasc Biol 1999;
19:378383.
400. Nofer JR, Tepel M, Kehrel B et al. High density lipoproteins
enhance the Na+/H+ antiport in human platelets. Thromb Haemost 1996;
75:635641.
401. Navab M, Berliner JA, Subbanagounder G et al. HDL and the
inflammatory response induced by LDL-derived oxidized phospholipids. Arterioscler
Thromb Vasc Biol 2001; 21:481488.
402. Parthasarathy S, Barnett J, Fong LG. High-density lipoprotein inhibits
the oxidative modification of low-density lipoprotein. Biochim Biophys
Acta 1990; 1044:275283.
403. Navab M, Hama SY, Cooke CJ. Normal high density lipoprotein inhibits
three steps in the formation of mildly oxidized low density lipoprotein: step
1. J Lipid Res 2000; 41:14811494.
404. Navab M, Hama SY, Anantharamaiah GM et al. Normal high density
lipoprotein inhibits three steps in the formation of mildly oxidized low density
lipoprotein: steps 2 and 3. J Lipid Res 2000; 41:14951508.
405. Hayek T, Oiknine J, Dankner G et al. HDL apolipoprotein A-I
attenuates oxidative modification of low density lipoprotein: studies in transgenic
mice. Eur J Clin Chem Clin Biochem 1995; 33:721725.
406. Gowri MS, Van der Westhuyzen DR, Bridges SR et al. Decreased
protection by HDL from poorly controlled type 2 diabetic subjects against
LDL oxidation may be due to the abnormal composition of HDL. Arterioscler
Thromb Vasc Biol 1999; 19:22262233.
407. Garner B, Waldeck AR, Witting PK et al. Oxidation of high
density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides
by methionine residues of apolipoproteins AI and AII. J Biol Chem 1998;
273:60886095.
408. Bowry VW, Stanley KK, Stocker R. High density lipoprotein is the
major carrier of lipid hydroperoxides in human blood plasma from fasting donors.
Proc Natl Acad Sci USA 1992; 89:1031610320.
409. Navab M, Hama SY, Reddy ST et al. Oxidized lipids as mediators
of coronary heart disease. Curr Opin Lipidol 2002; 13:363372.
410. Leitinger N. Oxidized phospholipids as modulators of inflammation
in atherosclerosis. Curr Opin Lipidol 2003; 14:421430.
411. Bochoov VN, Mechtcheriakova D, Lucerna M et al. Oxidized phospholipids
stimulate tissue factor expression in human endothelial cells via activation
of ERK/EGR-1 and Ca(++)/NFAT. Blood 2002; 99:199206.
412. Subbanagounder G, Wong JW, Lee H et al. Epoxyisoprostane and
epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1
and interleukin-8 synthesis. Formation of these oxidized phospholipids in
response to interleukin-1beta. J Biol Chem 2002; 277:72717281.
413. Subbanagounder G, Deny Y, Borromeo C et al. Hydroxy alkenal
phospholipids regulate inflammatory functions of endothelial cells. Vasc
Pharmacol 2002; 38:201209.
414. Pontsler AV, St Hilaire A, Marathe GK et al. Cyclooxygenase-2
is induced in monocytes by peroxisome proliferator activated receptor gamma
and oxidized alkyl phospholipids from oxidized low density lipoprotein. J
Biol Chem 2002; 277:1302913036.
415. Shih DM, Gu L, Hama S et al. Genetic-dietary regulation of
serum paraoxonase expression and its role in atherogenesis in a mouse model.
J Clin Invest 1996; 97:16301639.
416. Navab M, Anantharamaiah GM, Reddy ST et al. Human apolipoprotein
AI mimetic peptides for the treatment of atherosclerosis. Curr Opin
Investig Drugs 2003; 4:11001104.
417. Navab M, Anantharamaiah GM, Hama S et al. Oral administration
of an Apo A-I mimetic peptide synthesized from D-amino acids dramatically
reduces atherosclerosis in mice independent of plasma cholesterol. Circulation
2002; 105:290292.
418. Hedrick CC, Hassan K, Hough GP et al.
Short-term feeding
of atherogenic diet to mice results in reduction of HDL and paraoxonase that
may be mediated by an immune mechanism. Arterioscler
Thromb Vasc Biol 2000; 20:19461952.
419. Shih DM, Xia YR, Wang XP et al. Combined serum paraoxonase
knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation
and atherosclerosis. J Biol Chem 2000;
275:1752717535.
420. Shih DM, Gu L, Xia YR et al. Mice lacking serum paraoxonase
are susceptible to organophosphate toxicity and atherosclerosis. Nature 1998; 394:284287.
421. Oda MN, Bielicki JK, Ho TT et al. Paraoxonase 1 overexpression
in mice and its effect on high-density lipoproteins. Biochem Biophys Res Commun
2002; 290:921927.
422. Tward A, Xia YR, Wang XP et al. Decreased atherosclerotic
lesion formation in human serum paraoxonase transgenic mice. Circulation 2002;
106:484490.
423. Deakin S, Leviev I, Guernier S et al.
Simvastatin modulates
expression of the PON1 gene and increases serum paraoxonase: a role for sterol
regulatory element-binding protein-2. Arterioscler
Thromb Vasc Biol 2003; 23:20832089.
424. Tomas M, Senti M, Garcia-Faria F et al.
Effect of simvastatin
therapy on paraoxonase activity and related lipoproteins in familial hypercholesterolemic
patients. Arterioscler Thromb Vasc
Biol 2000; 20:21132119.
425. Adkins S, Gan KN, Mody M et al. Molecular basis for the
polymorphic forms of human serum paraoxonase/arylesterase: glutamine or arginine
at position 191, for the respective A or B allozymes. Am J Hum Genet 1993; 52:598608.
426. Humbert R, Adler DA, Disteche CM et al.
The molecular
basis of the human serum paraoxonase activity polymorphism. Nat Genet 1993; 3:7376.
427. Bauters C, Amant C, Boullier A et al.
Paraoxonase polymorphism
(Gln192Arg) as a determinant of the response of human coronary arteries to
serotonin. Circulation 2000;
101:740743.
428. Sanghera DK, Saha N, Aston CE et al.
Genetic polymorphism
of paraoxonase and the risk of coronary heart disease. Arterioscler Thromb Vasc Biol 1997;
17:10671073.
429. Wang X, Fan Z, Huang J et al. Extensive association analysis
between polymorphisms of PON gene cluster with coronary heart disease in Chinese
Han population. Arterioscler Thromb Vasc
Biol 2003; 23:328334.
430. Jarvik GP, Hatsukami TS, Carlson C et al.
Paraoxonase activity,
but not haplotype utilizing the linkage disequilibrium structure, predicts
vascular disease. Arterioscler Thromb Vasc
Biol 2003; 23:14651471.
431. Robertson KS, Hawe E, Miller GJ et al.
Human paraoxonase
gene cluster polymorphisms as predictors of coronary heart disease risk in
the prospective Northwick Part Heart Study II. Biochim Biophys Acta 2003; 1639:203212.
432. Quarck R, De Geest B, Stengel D et al. Adenovirus-mediated
gene transfer of human platelet-activating factor-acetylhydrolase prevents
injury-induced neointima formation and reduces spontaneous atherosclerosis
in apolipoprotein E-deficient mice. Circulation 2001; 103:24952500.
433. Yamada Y, Yoshida H, Ichihara S et al. Correlations between
plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH
genotype, age, and atherosclerosis in a Japanese population. Atherosclerosis
2000; 150:209216.
434. Tsimihodimos V, Karabina SA, Tambaki AP et al. Altered distribution
of platelet-activating factor-acetylhydrolase activity between LDL and HDL
as a function of the severity of hypercholesterolemia. J Lipid Res
2002; 43:256263.
435. Lee C, Sigari F, Segrado T et al. All ApoB-containing lipoproteins
induce monocyte chemotaxis and adhesion when minimally modified. Modulation
of lipoprotein bioactivity by platelet-activating factor acetylhydrolase.
Arterioscler Thromb Vasc Biol 1999; 19:14371446.
436. Langer C, Gansz B, Goepfert C et al. Testosterone up-regulates
scavenger receptor BI and stimulates cholesterol efflux from macrophages.
Biochem Biophys Res Commun 2002; 296:1051.
437. Harnish DC, Evans MJ, Scicchitano MS et al. Estrogen regulation
of the apolipoprotein AI gene promoter through transcription cofactor sharing.
J Biol Chem 1998; 273:92709278.
438. Funke H. Genetic determinants of high density lipoprotein levels.
Curr Opin Lipidol 1997; 8:189196.
439. von Eckardstein A, Assmann G. High density lipoproteins and reverse
cholesterol transport: lessons from mutations. Atherosclerosis 1998;
137(Suppl):S7S11.
440. Funke H. Familial HDL deficiency syndromes. In: Atherosclerosis
XI. Edited by B Jacotot, D Mathe and JC Fruchart. Singapore: Excerpta
Medica/Elsevier Science, 1997;713731.
441. Assmann G, von Eckardstein A, Funke H. High density lipoproteins,
reverse transport of cholesterol, and coronary artery disease. Insights from
mutations. Circulation 1993; 87(Suppl 3):III2834.
442. Assmann G, von Eckardstein A, Brewer HB Jr. Analphalipoproteinemia:
Tangier disease. In: The Metabolic and Molecular Bases of Inherited
Diseases. 8th edition. Edited by CR Scriver, AL Beaudet, WS Sly and D
Valle. New York: McGraw-Hill Publishing Company, 2001;29372960.
443. Hayden MR, Clee SM, Brooks-Wilson A et al. Cholesterol efflux
regulatory protein, Tangier disease and familial high-density lipoprotein
deficiency. Curr Opin Lipidol 2000; 11:117122.
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